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Golden, cheesy Chicken Alfredo Casserole in a white baking dish

Chicken Alfredo Casserole That Feeds the Soul

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A creamy, cheesy, and comforting Chicken Alfredo Casserole that’s quick to prepare and perfect for weeknight dinners. This family favorite blends tender chicken, penne pasta, and two kinds of cheese in a rich Alfredo sauce, all baked to golden perfection.

  • Total Time: 1 hour
  • Yield: 6 servings 1x

Ingredients

Scale

Main Ingredients

  • 3 skinless, boneless chicken breast halves
  • 1 (8 ounce) package penne pasta
  • ½ (16 ounce) jar Alfredo sauce
  • ¼ cup milk

Cheeses

  • 1 ½ cups shredded mozzarella cheese, divided
  • 1 cup shredded Cheddar cheese

Seasonings

  • 1 tablespoon onion powder
  • 1 tablespoon garlic powder

Instructions

  1. Cook the chicken: Bring a pot of water to a boil. Add the chicken breasts and simmer until fully cooked, about 20 minutes. Remove, shred, and set aside.
  2. Boil the pasta: In the same pot, cook the penne pasta until al dente. Drain and return to the pot.
  3. Mix the sauce: Stir in the Alfredo sauce, milk, onion powder, garlic powder, and 1 cup of mozzarella into the pasta. Add the shredded chicken and mix well.
  4. Assemble: Pour the mixture into a greased casserole dish. Sprinkle remaining mozzarella and the Cheddar cheese on top.
  5. Bake: Place in a preheated 350°F (175°C) oven for about 20 minutes, or until the top is golden and bubbly.

Notes

  • If the sauce is too thick, add more milk before baking.
  • Enhance the flavor with sautéed mushrooms or spinach.
  • Prepare in advance by assembling the casserole and refrigerating overnight.
  • Broil the top for 2 minutes at the end for extra crispiness.
  • Author: Chef Sofia
  • Prep Time: 20 minutes
  • Cook Time: 40 minutes
  • Category: Main-course
  • Method: Baking
  • Cuisine: American
  • Diet: Halal

Nutrition

  • Serving Size: 1 serving
  • Calories: 490
  • Sugar: 3g
  • Sodium: 680mg
  • Fat: 24g
  • Saturated Fat: 12g
  • Unsaturated Fat: 10g
  • Trans Fat: 0g
  • Carbohydrates: 35g
  • Fiber: 1g
  • Protein: 31g
  • Cholesterol: 95mg